Difference between revisions of "Radotinib (Supect)"
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Warner-admin (talk | contribs) m (Text replacement - "Category:Drug index" to "Category:Drugs") |
Warner-admin (talk | contribs) m (Text replacement - "Category:Chronic myelogenous leukemia" to "Category:Chronic myeloid leukemia") |
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==Diseases for which it is used== | ==Diseases for which it is used== | ||
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==Also known as== | ==Also known as== | ||
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[[Category:Oral medications]] | [[Category:Oral medications]] | ||
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[[Category:Bcr-Abl inhibitors]] | [[Category:Bcr-Abl inhibitors]] | ||
[[Category:PDGFR inhibitors]] | [[Category:PDGFR inhibitors]] | ||
| − | [[Category:Chronic | + | [[Category:Chronic myeloid leukemia medications]] |
[[Category:KFDA approved drugs]] | [[Category:KFDA approved drugs]] | ||
Latest revision as of 23:44, 26 September 2022
Not currently approved in the United States.
Mechanism of action
From the NCI Drug Dictionary: a second-generation tyrosine kinase inhibitor of Bcr-Abl fusion protein and the platelet-derived growth factor receptor (PDGFR), with potential antineoplastic activity. Upon administration, radotinib specifically inhibits the Bcr-Abl fusion protein, an abnormal enzyme expressed in Philadelphia chromosome-positive chronic myeloid leukemia (CML) cells. In addition, this agent also inhibits PDGFR thereby blocking PDGFR-mediated signal transduction pathways.
Diseases for which it is used
Also known as
- Code name: IY5511HCl
- Brand name: Supect