Difference between revisions of "Imetelstat (Rytelo)"
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Revision as of 04:52, 23 November 2014
Mechanism of action
A lipid-conjugated oligonucleotide inhibitor of human telomerase. Link to company website
Preliminary data
Myelofibrosis
- Abstract: Kebede Begna, Rebecca R. Laborde, Mrinal M Patnaik, Terra L Lasho, Darci Zblewski, Christy Finke, Lauren Schimek, Betsy R. LaPlant, Curtis A. Hanson, Monic J. Stuart, Animesh Pardanani. Imetelstat, a Telomerase Inhibitor, Induces Morphologic and Molecular Remissions In Myelofibrosis and Reversal Of Bone Marrow Fibrosis. Blood Nov 2013,122(21)662 link to original abstract