Difference between revisions of "Histrelin (Vantas)"
Jump to navigation
Jump to search
m (Text replacement - "[[Media:" to "[[File:") |
|||
| Line 1: | Line 1: | ||
==General information== | ==General information== | ||
| − | Class/mechanism: LH-RH agonist. Histrelin acetate inhibits gonadotropin secretion by desensitizing responsiveness of the pituitary gonadotropin which, in turn, causes a reduction in testicular steroidogenesis.<ref name="insert">[https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/021732s015lbl.pdf Histrelin (Vantas) package insert]</ref><ref>[[ | + | Class/mechanism: LH-RH agonist. Histrelin acetate inhibits gonadotropin secretion by desensitizing responsiveness of the pituitary gonadotropin which, in turn, causes a reduction in testicular steroidogenesis.<ref name="insert">[https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/021732s015lbl.pdf Histrelin (Vantas) package insert]</ref><ref>[[File:Histrelin.pdf | Histrelin (Vantas) package insert (locally hosted backup)]]</ref><ref>[http://www.vantasimplant.com/ Vantas implant manufacturer's website]</ref> |
<br>Route: SC | <br>Route: SC | ||
<br>Extravasation: no information | <br>Extravasation: no information | ||
Revision as of 23:33, 19 September 2021
General information
Class/mechanism: LH-RH agonist. Histrelin acetate inhibits gonadotropin secretion by desensitizing responsiveness of the pituitary gonadotropin which, in turn, causes a reduction in testicular steroidogenesis.[1][2][3]
Route: SC
Extravasation: no information
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the prescribing information.[1]
Diseases for which it is used
History of changes in FDA indication
- 10/12/2004: Initial FDA approval "in the palliative treatment of advanced prostate cancer."
Patient drug information
Also known as
- Generic name: histrelin acetate
- Brand names: Supprelin, Vantas