Difference between revisions of "Bevacizumab (Avastin)"

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For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer.  Instead, for the most current information, please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [http://online.lexi.com/ Lexicomp], [http://reference.medscape.com/drug/avastin-bevacizumab-342257 Medscape],[http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the prescribing information.<ref name="insert"></ref>
 
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer.  Instead, for the most current information, please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [http://online.lexi.com/ Lexicomp], [http://reference.medscape.com/drug/avastin-bevacizumab-342257 Medscape],[http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the prescribing information.<ref name="insert"></ref>
 
==Diseases for which it is used==
 
*[[Breast cancer]]
 
*[[Central nervous system (CNS) cancer]]
 
*[[Cervical cancer]]
 
*[[Colon cancer]]
 
*[[Esophageal cancer]]
 
*[[Hepatobiliary cancer]]
 
*[[Melanoma]]
 
*[[Neuroendocrine tumors]]
 
*[[Non-small cell lung cancer]]
 
*[[Ovarian cancer]]
 
*[[Renal cancer]]
 
*[[Sarcoma]]
 
*[[Unknown primary]]
 
*[[Uterine cancer]]
 
  
 
==Information about counterfeit Bevacizumab (Avastin)==
 
==Information about counterfeit Bevacizumab (Avastin)==
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[[Category:VEGF inhibitors]]
 
[[Category:VEGF inhibitors]]
 
[[Category:Breast cancer medications]]
 
[[Category:Breast cancer medications]]
 +
[[Category:Cancer of unknown primary medications]]
 +
[[Category:Central nervous system (CNS) cancer medications]]
 
[[Category:Cervical cancer medications]]
 
[[Category:Cervical cancer medications]]
 
[[Category:Colon cancer medications]]
 
[[Category:Colon cancer medications]]
 
[[Category:Esophageal cancer medications]]
 
[[Category:Esophageal cancer medications]]
 
[[Category:Hepatobiliary cancer medications]]
 
[[Category:Hepatobiliary cancer medications]]
 +
[[Category:Melanoma medications]]
 +
[[Category:Neuroendocrine tumor medications]]
 
[[Category:Non-small cell lung cancer medications]]
 
[[Category:Non-small cell lung cancer medications]]
 
[[Category:Ovarian cancer medications]]
 
[[Category:Ovarian cancer medications]]
 
[[Category:Renal cancer medications]]
 
[[Category:Renal cancer medications]]
[[Category:Cancer of unknown primary medications]]
+
[[Category:Sarcoma medications]]
 +
[[Category:Uterine cancer medications]]

Revision as of 17:17, 11 June 2014

General information

Class/mechanism: Monoclonal antibody that inhibits angiogenesis by binding VEGF and preventing the interaction of VEGF with its receptors (Flt-1 and KDR) on the surface of endothelial cells.[1][2][3]
Route: IV
Extravasation: no information

For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, Medscape,UpToDate (courtesy of Lexicomp), or the prescribing information.[1]

Information about counterfeit Bevacizumab (Avastin)

Patient drug information

References