Difference between revisions of "Tremelimumab (Imjudo)"
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==Also known as== | ==Also known as== | ||
− | *'''Code name:''' CP-675, | + | *'''Code name:''' CP-675, CP-675206 |
*'''Generic name:''' ticilimumab | *'''Generic name:''' ticilimumab | ||
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[[Category:Drugs]] | [[Category:Drugs]] | ||
[[Category:Intravenous medications]] | [[Category:Intravenous medications]] | ||
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[[Category:Anti-CTLA-4 antibodies]] | [[Category:Anti-CTLA-4 antibodies]] | ||
[[Category:Investigational drugs]] | [[Category:Investigational drugs]] |
Revision as of 02:37, 29 February 2020
General information
Class/mechanism: Anti-CTLA-4 antibody. CTLA-4 is a negative regulator of T-cell activation and ipilimumab interferes with the ability of CTLA-4 to interact with its ligands CD80/CD86. CTLA-4 blockade results in T-cell activation and proliferation, and it is suspected that its anti-neoplastic activity may be due to T-cell mediated anti-tumor immune responses.[1][2]
Route: IV
Extravasation: no information
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the prescribing information.
Also known as
- Code name: CP-675, CP-675206
- Generic name: ticilimumab