Difference between revisions of "Aminopterin"

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Revision as of 17:45, 3 February 2019

General information

Class/mechanism: Folate analog, antimetabolite, interferes with DNA synthesis. Discontinued due to concerns about toxicity, manufacturing difficulties, and rough equivalence to methotrexate. It remains under investigation for the non-neoplastic condition of psoriasis.
Route: IM

Diseases for which it was used