Difference between revisions of "Leuprolide (Lupron)"
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| − | Also known as Eligard, Lupron Depot, or Viadur. | + | Also known as Eligard, leuprolide acetate, Lupron Depot, Leuprorelin, or Viadur. |
==General information== | ==General information== | ||
| − | Class/mechanism: GnRH (gonadotropin-releasing hormone)/LHRH (luteinizing hormone releasing hormone) agonist; inhibits gonadotropin secretion, decreasing circulating levels of LH (luteinizing hormone) and FSH (follicle stimulating hormone), and suppressing synthesis of ovarian and testicular steroids.<ref name="insert">[http://www. | + | Class/mechanism: GnRH (gonadotropin-releasing hormone)/LHRH (luteinizing hormone releasing hormone) agonist; inhibits gonadotropin secretion, decreasing circulating levels of LH (luteinizing hormone) and FSH (follicle stimulating hormone), and suppressing synthesis of ovarian and testicular steroids.<ref name="insert">[http://www.rxabbvie.com/pdf/lupron7_5mg.pdf Leuprolide (Lupron) package insert]</ref><ref>[[Media:Leuprolidelupron.pdf|Leuprolide (Lupron>) package insert (locally hosted backup)]]</ref><ref>[http://www.lupron.com/ Lupron manufacturer's website]</ref><ref name="Eligard">[http://products.sanofi.us/eligard/eligard.pdf Leuprolide (Eligard) package insert]</ref><ref>[[Media:Leuprolideeligard.pdf|Leuprolide (Eligard) package insert (locally hosted backup)]]</ref><ref>[http://www.eligard.com Eligard manufacturer's website]</ref> |
<br>Route: IM | <br>Route: IM | ||
<br>Extravasation: n/a | <br>Extravasation: n/a | ||
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [http://online.lexi.com/ Lexicomp], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the prescribing information.<ref name="insert"></ref> | For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [http://online.lexi.com/ Lexicomp], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the prescribing information.<ref name="insert"></ref> | ||
| + | |||
| + | ==Diseases for which it is used== | ||
| + | *[[Prostate cancer]] | ||
==Patient drug information== | ==Patient drug information== | ||
| − | *[http://chemocare.com/ | + | *[http://chemocare.com/chemotherapy/drug-info/Leuprolide.aspx Leuprolide (Lupron) patient drug information (Chemocare)]<ref>[http://chemocare.com/chemotherapy/drug-info/Leuprolide.aspx Leuprolide (Lupron) patient drug information (Chemocare)]</ref> |
| + | *Brief patient counseling information can be found on [http://products.sanofi.us/eligard/eligard.pdf#page=7 page 7 of the Leuprolide (Eligard) package insert]<ref name="Eligard"></ref> | ||
*[http://www.uptodate.com/contents/leuprolide-patient-drug-information Leuprolide (Lupron) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/leuprolide-patient-drug-information Leuprolide (Lupron) patient drug information (UpToDate)]</ref> | *[http://www.uptodate.com/contents/leuprolide-patient-drug-information Leuprolide (Lupron) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/leuprolide-patient-drug-information Leuprolide (Lupron) patient drug information (UpToDate)]</ref> | ||
==References== | ==References== | ||
<references/> | <references/> | ||
| + | |||
| + | [[Category:Drug index]] | ||
| + | [[Category:Antiandrogens]] | ||
| + | [[Category:GnRH agonists]] | ||
| + | [[Category:Prostate cancer medications]] | ||
Revision as of 23:28, 22 February 2013
Also known as Eligard, leuprolide acetate, Lupron Depot, Leuprorelin, or Viadur.
General information
Class/mechanism: GnRH (gonadotropin-releasing hormone)/LHRH (luteinizing hormone releasing hormone) agonist; inhibits gonadotropin secretion, decreasing circulating levels of LH (luteinizing hormone) and FSH (follicle stimulating hormone), and suppressing synthesis of ovarian and testicular steroids.[1][2][3][4][5][6]
Route: IM
Extravasation: n/a
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the prescribing information.[1]
Diseases for which it is used
Patient drug information
- Leuprolide (Lupron) patient drug information (Chemocare)[7]
- Brief patient counseling information can be found on page 7 of the Leuprolide (Eligard) package insert[4]
- Leuprolide (Lupron) patient drug information (UpToDate)[8]
References
- ↑ 1.0 1.1 Leuprolide (Lupron) package insert
- ↑ Leuprolide (Lupron>) package insert (locally hosted backup)
- ↑ Lupron manufacturer's website
- ↑ 4.0 4.1 Leuprolide (Eligard) package insert
- ↑ Leuprolide (Eligard) package insert (locally hosted backup)
- ↑ Eligard manufacturer's website
- ↑ Leuprolide (Lupron) patient drug information (Chemocare)
- ↑ Leuprolide (Lupron) patient drug information (UpToDate)