Difference between revisions of "Thrombocytosis"
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==Definition== | ==Definition== | ||
Revision as of 13:48, 1 February 2018
Use of this site is subject to you reading and agreeing with the terms set forth in the disclaimer. If this is your first time visiting, we suggest you read the tutorial.
Definition
Platelet count greater than or equal to 450 × 109/L (local reference ranges may vary).[1]
Initial evaluation
May consist of:
- CBC with differential
- Iron, total iron binding capacity (TIBC), ferritin
- JAK2 V617F mutation
- CALR exon 9 indels
- MPL exon 10 mutations
- Peripheral smear
- Clinical history (e.g. recent surgery or other reasons for reactive thrombocytosis), lifestyle factors
References
- ↑ Elisa Rumi and Mario Cazzola. How I treat essential thrombocythemia. Blood 2016 128:2403-2414. PubMed