Difference between revisions of "Breast cancer BRCA1 & BRCA2 genetic testing"
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=Criteria for BRCA1/BRCA2 genetic testing= | =Criteria for BRCA1/BRCA2 genetic testing= | ||
| − | ''This is from a clinical trial protocol and is similar to, but not identical to, the NCCN breast cancer familiar risk assessment guidelines.'' | + | ''This is from a clinical trial protocol and is similar to, but not identical to, the NCCN breast cancer familiar risk assessment guidelines.''<ref>[http://www.nccn.org/professionals/physician_gls/pdf/genetics_screening.pdf NCCN Guidelines for Breast and/or Ovarian Genetic Assessment]</ref> Additional resources can be found at the links below.<ref>[http://www.cancer.gov/cancertopics/factsheet/Risk/BRCA BRCA1 and BRCA2: Cancer Risk and Genetic Testing] (cancer.gov)</ref><ref>[http://www.uspreventiveservicestaskforce.org/uspstf/uspsbrgen.htm U.S. Preventive Services Task Force (USPSTF) Genetic Risk Assessment and BRCA Mutation Testing for Breast and Ovarian Cancer Susceptibility]</ref> |
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*Breast cancer diagnosed ≤45 years old | *Breast cancer diagnosed ≤45 years old | ||
*Diagnosed at age ≤50 years old with: | *Diagnosed at age ≤50 years old with: | ||
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*Male breast cancer | *Male breast cancer | ||
*First, second, or third-degree male relative with breast cancer | *First, second, or third-degree male relative with breast cancer | ||
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| + | ==References== | ||
| + | <references /> | ||
Revision as of 03:33, 22 January 2013
Use of this site is subject to you reading and agreeing with the terms set forth in the disclaimer.
Criteria for BRCA1/BRCA2 genetic testing
This is from a clinical trial protocol and is similar to, but not identical to, the NCCN breast cancer familiar risk assessment guidelines.[1] Additional resources can be found at the links below.[2][3]
- Breast cancer diagnosed ≤45 years old
- Diagnosed at age ≤50 years old with:
- first, second, or third-degree blood relative with breast cancer diagnosis ≤50 years old
- and/or epithelial ovarian or fallopian peritoneal cancer at any age
- Diagnosed at age <60 years old with a triple negative breast cancer
- Two breast primaries--that is, bilateral disease or two or more clearly separate ipsilateral primary tumors--when first breast cancer diagnosis occurred prior to age 50
- Personal history of epithelial ovarian, fallopian tube, or primary peritoneal cancer
- Diagnosed at any age with ≥2 first, second, or third-degree relatives with breast and/or epithelial ovarian, fallopian tube, or primary peritoneal cancer at any age
- First or second-degree relative of anybody known to carry a harmful BRCA1 or BRCA2 mutation
- Ashkenazi Jewish descent
- Male breast cancer
- First, second, or third-degree male relative with breast cancer