Difference between revisions of "Bacillus Calmette-Guérin (BCG, TheraCys)"

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==General information==
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#REDIRECT [[Bacillus Calmette-Guerin (BCG)]]
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Class/mechanism: Live mycobacteria which promote a local acute inflammatory and sub-acute granulomatous reaction with macrophage and leukocyte infiltration in the urothelium and lamina propria of the urinary bladder.  This results in a likely T-lymphocyte dependent anti-tumor effect.<ref name="insert">[https://www.vaccineshoppecanada.com/secure/pdfs/ca/immucyst_e.pdf Bacillus Calmette-Guerin (BCG) package insert]</ref><ref>[http://hemonc.org/docs/packageinsert/bacilluscalmetteguerin.pdf Bacillus Calmette-Guerin (BCG) package insert (locally hosted backup)]</ref>
 
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<br>Route: Intravesicular
 
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<br>Extravasation: n/a
 
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For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer.  Instead, for the most current information, please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [http://online.lexi.com/ Lexicomp], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the prescribing information.<ref name="insert"></ref>
 
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==Patient drug information==
 
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*[http://chemocare.com/bio/bcg.asp Bacillus Calmette-Guerin (BCG, TheraCys) patient drug information (Chemocare)]<ref>[http://chemocare.com/bio/bcg.asp Bacillus Calmette-Guerin (BCG, TheraCys) patient information (Chemocare)]</ref>
 
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*[http://www.uptodate.com/contents/patient-information-bladder-cancer-treatment-non-muscle-invasive-superficial-cancer Patient information about bladder cancer treatment, including BCG (UpToDate)]<ref>[http://www.uptodate.com/contents/patient-information-bladder-cancer-treatment-non-muscle-invasive-superficial-cancer Patient information about bladder cancer treatment, including BCG (UpToDate)]</ref>
 
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==References==
 
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<references/>
 

Revision as of 17:40, 7 October 2012

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