Difference between revisions of "Anagrelide (Agrylin)"
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| + | Also known as Xagrid. | ||
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==General information== | ==General information== | ||
| − | Class/mechanism: Interferes with maturation of platelets from megakaryocytes, phosphodiesterase inhibitor.<ref name="insert">[http://www.shire.com/shireplc/dlibrary/documents/AgrylinUSPIAug2009.pdf Anagrelide (Agrylin) package insert]</ref><ref>[ | + | Class/mechanism: Interferes with maturation of platelets from megakaryocytes, phosphodiesterase inhibitor.<ref name="insert">[http://www.shire.com/shireplc/dlibrary/documents/AgrylinUSPIAug2009.pdf Anagrelide (Agrylin) package insert]</ref><ref>[[Media:Anagrelide.pdf | Anagrelide (Agrylin) package insert (locally hosted backup)]]</ref> |
<br>Route: PO | <br>Route: PO | ||
<br>Extravasation: n/a | <br>Extravasation: n/a | ||
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| + | *Example of usage: Anagrelide (Agrylin) 0.5 mg PO 4 times per day or 1 mg PO twice per day, titrate to the lowest effective dose to maintain platelets below 600,000, maximum increase in dose of 0.5 mg/day every week (max dose: 10 mg/day, 2.5 mg in a single dose) | ||
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [http://online.lexi.com/ Lexicomp], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the prescribing information.<ref name="insert"></ref> | For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [http://online.lexi.com/ Lexicomp], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the prescribing information.<ref name="insert"></ref> | ||
==Patient drug information== | ==Patient drug information== | ||
| − | *[http://chemocare.com/ | + | *[http://chemocare.com/chemotherapy/drug-info/anagrelide.aspx Anagrelide (Agrylin) patient drug information (Chemocare)]<ref>[http://chemocare.com/chemotherapy/drug-info/anagrelide.aspx Anagrelide (Agrylin) patient drug information (Chemocare)]</ref> |
*[http://www.uptodate.com/contents/anagrelide-patient-drug-information Anagrelide (Agrylin) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/anagrelide-patient-drug-information Anagrelide (Agrylin) patient drug information (UpToDate)]</ref> | *[http://www.uptodate.com/contents/anagrelide-patient-drug-information Anagrelide (Agrylin) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/anagrelide-patient-drug-information Anagrelide (Agrylin) patient drug information (UpToDate)]</ref> | ||
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==References== | ==References== | ||
<references/> | <references/> | ||
Revision as of 03:28, 7 October 2012
Also known as Xagrid.
General information
Class/mechanism: Interferes with maturation of platelets from megakaryocytes, phosphodiesterase inhibitor.[1][2]
Route: PO
Extravasation: n/a
- Example of usage: Anagrelide (Agrylin) 0.5 mg PO 4 times per day or 1 mg PO twice per day, titrate to the lowest effective dose to maintain platelets below 600,000, maximum increase in dose of 0.5 mg/day every week (max dose: 10 mg/day, 2.5 mg in a single dose)
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the prescribing information.[1]
Patient drug information
- Anagrelide (Agrylin) patient drug information (Chemocare)[3]
- Anagrelide (Agrylin) patient drug information (UpToDate)[4]