Difference between revisions of "Example orders for Cetuximab (Erbitux) in colon cancer"

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Monitoring:
 
Monitoring:
*Physician to be notified if ANC <1000 or platelets <100.  
+
*Hold if ANC <1000 or platelets <100 and notify physician.
 
 
For cycle 2 and later:
 
For cycle 2 and later:
 
*[[Cetuximab (Erbitux)]] 250 mg/m2 IV over 60 minutes on days 1, 8, 15, 22
 
*[[Cetuximab (Erbitux)]] 250 mg/m2 IV over 60 minutes on days 1, 8, 15, 22
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Monitoring:
 
Monitoring:
*Physician to be notified if ANC <1000 or platelets <100.  
+
*Hold if ANC <1000 or platelets <100 and notify physician.
  
 
'''Comments:'''
 
'''Comments:'''
 
*My institution uses 28-day cycles for Cetuximab (Erbitux) regimens.
 
*My institution uses 28-day cycles for Cetuximab (Erbitux) regimens.

Revision as of 04:56, 3 July 2012

Use of this site is subject to you reading and agreeing with the terms set forth in the disclaimer.


Cetuximab (Erbitux)

Original reference may be found at Cetuximab (Erbitux)

Example regimen #1

For cycle 1:

28-day cycle

Supportive medications:

  • Acetaminophen (Tylenol) 650 mg PO 30 minutes prior to cetuximab
  • Diphenhydramine (Benadryl) 50 mg IV 30 minutes prior to cetuximab

Hydration:

  • 500 ml NS at KVO rate as running IV for chemotherapy infusion. Give up to 500 ml NS.

Monitoring:

  • Hold if ANC <1000 or platelets <100 and notify physician.

For cycle 2 and later:

  • Cetuximab (Erbitux) 250 mg/m2 IV over 60 minutes on days 1, 8, 15, 22
    • Use non-DEHP/paclitaxel tubing.

28-day cycles

Supportive medications:

  • Acetaminophen (Tylenol) 650 mg PO 30 minutes prior to cetuximab
  • Diphenhydramine (Benadryl) 50 mg IV 30 minutes prior to cetuximab

Hydration:

  • 500 ml NS at KVO rate as running IV for chemotherapy infusion. Give up to 500 ml NS.

Monitoring:

  • Hold if ANC <1000 or platelets <100 and notify physician.

Comments:

  • My institution uses 28-day cycles for Cetuximab (Erbitux) regimens.