Difference between revisions of "Thrombocytosis"

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==Definition==
 
==Definition==
Platelet count ≥450 × 109/L.<ref>Elisa Rumi and Mario Cazzola. [http://www.bloodjournal.org/content/128/20/2403 How I treat essential thrombocythemia.] Blood 2016 128:2403-2414. [https://www.ncbi.nlm.nih.gov/pubmed/27561316 PubMed]</ref>
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Platelet count greater than or equal to 450 × 10<sup>9</sup>/L (''local reference ranges may vary'').<ref>Elisa Rumi and Mario Cazzola. [http://www.bloodjournal.org/content/128/20/2403 How I treat essential thrombocythemia.] Blood 2016 128:2403-2414. [https://www.ncbi.nlm.nih.gov/pubmed/27561316 PubMed]</ref>
  
 
==Initial evaluation==
 
==Initial evaluation==
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==References==
 
==References==
 
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[[Category:Hematology reference pages]]

Revision as of 03:16, 25 July 2017

Use of this site is subject to you reading and agreeing with the terms set forth in the disclaimer.

Definition

Platelet count greater than or equal to 450 × 109/L (local reference ranges may vary).[1]

Initial evaluation

May consist of:

  • CBC with differential
  • Iron, total iron binding capacity (TIBC), ferritin
  • JAK2 V617F mutation
  • CALR exon 9 indels
  • MPL exon 10 mutations
  • Peripheral smear
  • Clinical history (e.g. recent surgery or other reasons for reactive thrombocytosis), lifestyle factors

References

  1. Elisa Rumi and Mario Cazzola. How I treat essential thrombocythemia. Blood 2016 128:2403-2414. PubMed