View source for Melphalan for Injection-Hepatic Delivery System (Hepzato Kit)

==General information==
Class/mechanism: Nitrogen mustard, alkylator

==Diseases for which it is established==
*[[Uveal melanoma]]

==History of changes in FDA indication==
*2023-08-14: Initial approval as a liver-directed treatment for adult patients with [[uveal melanoma]] with unresectable hepatic metastases affecting less than 50% of the liver and no extrahepatic disease, or extrahepatic disease limited to the bone, lymph nodes, subcutaneous tissues, or lung that is amenable to resection or radiation. ''(Based on FOCUS<sub>HCC</sub>)''

==Also known as==
*'''Brand name:''' Hepzato

==References==
#FOCUS<sub>HCC</sub>: NCT02678572

[[Category:Drugs]]
[[Category:Intra-arterial medications]]

[[Category:Alkylating agents]]
[[Category:Nitrogen mustards]]

[[Category:Uveal melanoma medications]]
[[Category:FDA approved in 2023]]
[[Category:Stub]]