Difference between revisions of "Antithymocyte globulin, rabbit ATG (Thymoglobulin)"
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==Diseases for which it is used== | ==Diseases for which it is used== | ||
*[[Aplastic anemia]] | *[[Aplastic anemia]] | ||
| + | *[[Graft versus host disease (GVHD)]] | ||
*[[Myelodysplastic syndrome]] | *[[Myelodysplastic syndrome]] | ||
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==Patient drug information== | ==Patient drug information== | ||
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<references/> | <references/> | ||
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[[Category:Fractionated plasma products]] | [[Category:Fractionated plasma products]] | ||
[[Category:Intravenous medications]] | [[Category:Intravenous medications]] | ||
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[[Category:Antithymocyte globulin]] | [[Category:Antithymocyte globulin]] | ||
[[Category:Aplastic anemia medications]] | [[Category:Aplastic anemia medications]] | ||
[[Category:Myelodysplastic syndrome medications]] | [[Category:Myelodysplastic syndrome medications]] | ||
| − | [[Category:GVHD medications]] | + | [[Category:Graft versus host disease (GVHD) medications]] |
Revision as of 18:44, 30 July 2018
General information
Class/mechanism: Contains antibodies against T-cell markers including CD2, CD3, CD4, CD8, CD11a, CD18, CD25, CD44, CD45, Beta-2 microglobulin, HLA Class I heavy chains, and HLA-DR. Exact mechanism not understood, but may involve removing T-cells from circulation and modifying T-cell activation, migration, proliferation, and cytotoxic effects.[1][2][3]
Route: IV
Extravasation: no information
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, Medscape, UpToDate (courtesy of Lexicomp), or the prescribing information.[1]
Diseases for which it is used
Patient drug information
Also known as
- Generic names: anti-thymocyte globulin (rabbit), antithymocyte globulin (rabbit), lymphocyte immune globulin (rabbit)
- Brand name: Thymoglobulin