Von Willebrand factor and factor VIII complex, human
General information
Class/mechanism: Von Willebrand Factor (vWF) and coagulation factor VIII complex; allows for improved platelet function & coagulation in patients with von Willebrand Disease (vWD) and/or hemophilia A. VWF mediates binding between platelets and damaged endothelial tissue in addition to functioning as a carrier protein for factor VIII, which is a participant in the coagulation cascade.
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Route: IV
Extravasation: no information
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the prescribing information.
Patient drug information
Also known as
- Generic name: antihemophilic factor/von Willebrand Factor complex
- Brand names: Alphanate, Humate-P, Wilate, Wilfactin
References
- ↑ Von Willebrand Factor and factor VIII complex, human (Alphanate) package insert
- ↑ Von Willebrand Factor and factor VIII complex, human (Alphanate) (locally hosted backup)
- ↑ Humate-P manufacturer's website
- ↑ Von Willebrand Factor and factor VIII complex, human (Humate-P) package insert
- ↑ Von Willebrand Factor and factor VIII complex, human (Humate-P) (locally hosted backup)
- ↑ Wilate manufacturer's website
- ↑ Von Willebrand Factor and factor VIII complex, human (Wilate) package insert
- ↑ Von Willebrand Factor and factor VIII complex, human (Wilate) (locally hosted backup)
- ↑ Von Willebrand Factor and factor VIII complex, human patient drug information (UpToDate)