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Folinic acid (Leucovorin)

157 bytes added, 22:38, 15 January 2012
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==General information==
Class/mechanism: Folic acid analog; counteracts the effects of folic acid antagonists such as methotrexate, which acts by inhibiting dihydrofolate reductase.<ref name="insert">[http://patient.cancerconsultants.com/druginserts/Leucovorin_inj.pdf Folinic acid (Leucovorin) package insert]</ref><ref>[http://hemonc.org/docs/packageinsert/folinicacid.pdf Folinic acid (Leucovorin) package insert (locally hosted backup)]</ref><br>Route: TBDPO, IM, IV<br>Extravasation: TBDno information
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [http://online.lexi.com/ Lexicomp], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the package insert<ref name="insert"></ref>.
==Patient drug information==
*[http://chemocare.com/bio/folinic_acid.asp Folinic acid (Leucovorin) patient drug information (Chemocare)]<ref>[http://chemocare.com/bio/folinic_acid.asp Folinic acid (Leucovorin) patient drug information (Chemocare)]</ref>
*[http://www.uptodate.com/contents/folinicacidleucovorin-patient-drug-information Folinic acid (Leucovorin) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/folinicacidleucovorin-patient-drug-information Folinic acid (Leucovorin) patient drug information (UpToDate)]</ref>
==References==
<references/>
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