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B-cell acute lymphoblastic leukemia - historical

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L-Asparaginase, Vincristine, Prednisone {{#subobject:d039d8|Regimen=1}}
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===Regimen {{#subobject:a4174a|Variant=1}}===
{| class="wikitable" style="width: 100%; text-align:center;"
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|[https://www.ncbi.nlm.nih.gov/pubmed/2665546 van der Does-van den Berg et al. 1989 (DCLSG ALL V)]
|style="background-color:#1a9851"|Phase III (C)
|[[B-cell_acute_lymphoblastic_leukemia#Daunorubicin.2C_L-Asparaginase.2C_Vincristine.2C_Prednisone|Daunorubicin, L-Asparaginase, Vincristine, Prednisone]]
|style="background-color:#ffffbf"|Seems not superior
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|[https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1365-2141.1991.tb04415.x Eden et al. 1991 (MRC UKALL VIII)]
|style="background-color:#1a9851"|Phase III (C)
|[[B-cell_acute_lymphoblastic_leukemia#Daunorubicin.2C_L-Asparaginase.2C_Vincristine.2C_Prednisone|Daunorubicin, L-Asparaginase, Vincristine, Prednisone]]
# Gottlieb AJ, Weinberg V, Ellison RR, Henderson ES, Terebelo H, Rafla S, Cuttner J, Silver RT, Carey RW, Levy RN, Hutchinson JL, Raich P, Cooper MR, Wiernik P, Anderson JR, Holland JF. Efficacy of daunorubicin in the therapy of adult acute lymphocytic leukemia: a prospective randomized trial by Cancer and Leukemia Group B. Blood. 1984 Jul;64(1):267-74. [http://www.bloodjournal.org/content/64/1/267.long link to original article] [https://www.ncbi.nlm.nih.gov/pubmed/6375760 PubMed]
# '''DCLSG ALL V:''' van der Does-van den Berg A, van Wering ER, Suciu S, Solbu G, van 't Veer MB, Rammeloo JA, de Koning J, van Zanen GE. Effectiveness of rubidomycin in induction therapy with vincristine, prednisone, and L-asparaginase for standard risk childhood acute lymphocytic leukemia: results of a Dutch phase III study (ALL V); A report on behalf of the Dutch Childhood Leukemia Study Group (DCLSG). Am J Pediatr Hematol Oncol. 1989 Summer;11(2):125-33. [https://www.ncbi.nlm.nih.gov/pubmed/2665546 PubMed]
# '''MRC UKALL VIII:''' Eden OB, Lilleyman JS, Richards S, Shaw MP, Peto J. Results of Medical Research Council Childhood Leukaemia Trial UKALL VIII (report to the Medical Research Council on behalf of the Working Party on Leukaemia in Childhood). Br J Haematol. 1991 Jun;78(2):187-96. [https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1365-2141.1991.tb04415.x link to original article] [https://www.ncbi.nlm.nih.gov/pubmed/2064956 PubMed]
# '''CCG-1922:''' Bostrom BC, Sensel MR, Sather HN, Gaynon PS, La MK, Johnston K, Erdmann GR, Gold S, Heerema NA, Hutchinson RJ, Provisor AJ, Trigg ME; Children's Cancer Group. Dexamethasone versus prednisone and daily oral versus weekly intravenous mercaptopurine for patients with standard-risk acute lymphoblastic leukemia: a report from the Children's Cancer Group. Blood. 2003 May 15;101(10):3809-17. Epub 2003 Jan 16. [http://www.bloodjournal.org/content/101/10/3809.long link to original article] [https://www.ncbi.nlm.nih.gov/pubmed/12531809 PubMed]
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