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Argatroban (Acova)

27 bytes removed, 10:57, 7 October 2012
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==General information==
Class/mechanism: Direct thrombin inhibitor, binds reversibly to free and clot-associated thrombin and inhibits its effects of catalyzing the formation of fibrin from fibrinogen, platelet aggregation, activation of protein C, and activation of coagulation factors V, VIII, and XIII.<ref name="insert">[https://www.gsksource.com/gskprm/htdocs/documents/ARGATROBAN.PDF Argatroban package insert]</ref><ref>[http[Media://hemonc.org/docs/packageinsert/argatrobanArgatroban.pdf | Argatroban package insert (locally hosted backup)]]</ref><ref>[http://www.gsksource.com/gskprm/en/US/adirect/gskprm?cmd=ProductDetailPage&product_id=1244136535577 Argatroban manufacturer's website]</ref>
<br>Route: IV
<br>Extravasation: no information
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