Cisplatin & Gemcitabine in all diseases
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Bladder cancer, neoadjuvant
Source: Cisplatin & Gemcitabine for bladder cancer, neoadjuvant
GC: Gemcitabine, Cisplatin
Regimen variant #1, single-dose cisplatin
Study | Evidence |
---|---|
Dash et al. 2008 | Retrospective |
Chemotherapy
- Cisplatin (Platinol) 70 mg/m2 IV once on day 1
- Gemcitabine (Gemzar) 1000 mg/m2 IV once per day on days 1 & 8
21-day cycle for 4 cycles
Subsequent treatment
Regimen variant #2, split-dose cisplatin
Study | Evidence |
---|---|
Dash et al. 2008 | Retrospective |
Chemotherapy
- Cisplatin (Platinol) 35 mg/m2 IV once per day on days 1 & 8
- Gemcitabine (Gemzar) 1000 mg/m2 IV once per day on days 1 & 8
21-day cycle for 4 cycles
Subsequent treatment
References
- Retrospective: Dash A, Pettus JA 4th, Herr HW, Bochner BH, Dalbagni G, Donat SM, Russo P, Boyle MG, Milowsky MI, Bajorin DF. A role for neoadjuvant gemcitabine plus cisplatin in muscle-invasive urothelial carcinoma of the bladder: a retrospective experience. Cancer. 2008 Nov 1;113(9):2471-7. link to PMC article contains verified protocol PubMed