Bavituximab (PGN401)

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Mechanism of action

Binds to phosphatidylserine, provoking an immune response.

Preliminary data

Non-small cell lung cancer

  1. Digumarti R, Bapsy PP, Suresh AV, Bhattacharyya GS, Dasappa L, Shan JS, Gerber DE. Bavituximab plus paclitaxel and carboplatin for the treatment of advanced non-small-cell lung cancer. Lung Cancer. 2014 Nov;86(2):231-6. Epub 2014 Aug 24. link to original article PubMed