Regimens that have not proven to be superior to a standard-of-care comparison and are thus unlikely to be expanded upon unless new evidence comes forward. This page is primarily to drive the HemOnc Ontology and for historic interest.

Regimens composed solely of approved drugs

CapeOx & Cediranib

Regimen

Chemotherapy

Targeted therapy

Cediranib (Recentin)

CapeOx & Cetuximab

Regimen

Chemotherapy

Targeted therapy

Cetuximab (Erbitux)

CapeOx & Lapatinib

Regimen

Chemotherapy

Targeted therapy

Lapatinib (Tykerb)

CapeOx & RT

Regimen

Chemotherapy

Radiotherapy

External beam radiotherapy

CapeOx & Tislelizumab

Regimen

Chemotherapy

Immunotherapy

Tislelizumab (Baizean)

CapeOx, Bevacizumab, Cetuximab

Regimen

Chemotherapy

Targeted therapy

Carboplatin & Docetaxel (DCb) & Celecoxib

Regimen

Chemotherapy

Carboplatin & Docetaxel (DCb) & Cetuximab

Regimen

Chemotherapy

Targeted therapy

Cetuximab (Erbitux)

Carboplatin & Docetaxel (DCb) & Farletuzumab

Regimen

Chemotherapy

Targeted therapy

Farletuzumab (MORAb-003)

Carboplatin & Etoposide (CE) & Adebrelimab

Regimen

Chemotherapy

Targeted therapy

Adebrelimab (SHR-1316)

Carboplatin & Gemcitabine (GCb), Atezolizumab, Bevacizumab

Regimen

Chemotherapy

Immunotherapy

Atezolizumab (Tecentriq)

Targeted therapy

Bevacizumab (Avastin)

Carboplatin & Gemcitabine (GCb)/Erlotinib

Regimen

Chemotherapy

Targeted therapy

Erlotinib (Tarceva)

Carboplatin & Paclitaxel (CP) & Avelumab

Regimen

Chemotherapy

Immunotherapy

Avelumab (Bavencio)

Carboplatin & Paclitaxel (CP) & Gefitinib

Regimen

Chemotherapy

Targeted therapy

Gefitinib (Iressa)

Carboplatin & Paclitaxel (CP) & Interferon gamma-1b

Regimen

Chemotherapy

Immunotherapy

Interferon gamma-1b (Actimmune)

Carboplatin & Paclitaxel (CP), Bevacizumab, Cetuximab

Regimen

Chemotherapy

Targeted therapy

Carboplatin & Paclitaxel (CP), Cetuximab, RT

Regimen

Chemotherapy

Targeted therapy

Cetuximab (Erbitux)

Radiotherapy

External beam radiotherapy

Carboplatin, Lenvatinib, Pemetrexed, Pembrolizumab

Regimen

Chemotherapy

Immunotherapy

Pembrolizumab (Keytruda)

Targeted therapy

Lenvatinib (Lenvima)

Carboplatin, Vindesine, RT

Regimen

Chemotherapy

Radiotherapy

External beam radiotherapy

Carfilzomib & Ibrutinib

Regimen

Targeted therapy

Chlorambucil, Cisplatin, Doxorubicin

Regimen

Chemotherapy

Cisplatin & Docetaxel (DC) & Bevacizumab

Regimen

Chemotherapy

Targeted therapy

Bevacizumab (Avastin)

Cisplatin & Docetaxel (DC) & Cetuximab

Regimen

Chemotherapy

Targeted therapy

Cetuximab (Erbitux)

Cisplatin & Etoposide (EP) & Paclitaxel

Regimen

Chemotherapy

Cisplatin & Etoposide (EP) & Pravastatin

Regimen

Chemotherapy

Cisplatin & Etoposide (EP) & RT

Regimen

Chemotherapy

Radiotherapy

External beam radiotherapy

Cisplatin & Etoposide (EP)/Topotecan monotherapy

Regimen

Chemotherapy

Cisplatin & Fluorouracil (CF) & Bevacizumab

Regimen

Chemotherapy

Targeted therapy

Bevacizumab (Avastin)

Cisplatin & Fluorouracil (CF), Interferon alfa-2b, RT

Regimen

Chemotherapy

Immunotherapy

Interferon alfa-2b (Intron-A)

Radiotherapy

External beam radiotherapy

Cisplatin & Fluorouracil (CF), Lenvatinib, Pembrolizumab

Regimen

Chemotherapy

Immunotherapy

Pembrolizumab (Keytruda)

Targeted therapy

Lenvatinib (Lenvima)

Cisplatin & Fluorouracil (CF), Pembrolizumab, Trastuzumab

Regimen

Chemotherapy

Immunotherapy

Pembrolizumab (Keytruda)

Targeted therapy

Trastuzumab (Herceptin)

Cisplatin & Irinotecan (IC) & Cetuximab

Regimen

Chemotherapy

Targeted therapy

Cetuximab (Erbitux)

Cisplatin, Nintedanib, Pemetrexed

Regimen

Chemotherapy

Targeted therapy

Nintedanib (Vargatef)

Cisplatin, Paclitaxel, Cetuximab, RT

Regimen

Chemotherapy

Targeted therapy

Cetuximab (Erbitux)

Radiotherapy

External beam radiotherapy

Cisplatin, Paclitaxel, Erlotinib, RT

Regimen

Chemotherapy

Targeted therapy

Erlotinib (Tarceva)

Radiotherapy

External beam radiotherapy

Cisplatin, Paclitaxel, Lenvatinib, Pembrolizumab

Regimen

Chemotherapy

Immunotherapy

Pembrolizumab (Keytruda)

Targeted therapy

Lenvatinib (Lenvima)

Cisplatin, Paclitaxel, Tislelizumab, RT

Regimen

Chemotherapy

Immunotherapy

Tislelizumab (Baizean)

Radiotherapy

External beam radiotherapy

3M

3M: Mitomycin, Mitoxantrone, Methotrexate

Regimen

Chemotherapy

4d+7

Regimen

Chemotherapy

4i+7

Regimen

Chemotherapy

5-FU & RT

Regimen

Chemotherapy

Fluorouracil (5-FU)

Radiotherapy

Concurrent radiation therapy

5-FU, Cyclophosphamide, Dactinomycin

Regimen

Chemotherapy

7+2d

Regimen

Chemotherapy

7+3a

Regimen

Chemotherapy

7+3d & Azacitidine

Regimen

Chemotherapy

7+3d & GM-CSF

Regimen

Chemotherapy

Growth factor therapy

Sargramostim (Leukine)

7+3d & Zosuquidar

Regimen

Chemotherapy

7+3i & Clofarabine

7+3i & Clofarabine: 7 days of cytarabine, 3 days of idarubicin, Clofarabine

Regimen

Chemotherapy

7+3i & Lenalidomide

7+3i & Lenalidomide: 7 days of cytarabine, 3 days of idarubicin, Lenalidomide

Regimen

Chemotherapy

Targeted therapy

Lenalidomide (Revlimid)

7+4d

Regimen

Chemotherapy

7+4i

7+4i: 7 days of cytarabine, 4 days of idarubicin

Regimen

Chemotherapy

7+5d

7+5d: 7 days of cytarabine, 5 days of daunorubicin

Regimen

Chemotherapy

7+5i & Quinine

Regimen

Chemotherapy

10+3d

Regimen

Chemotherapy

A-C

Regimen

Chemotherapy

A-CHOP-14

Regimen

Chemotherapy

Glucocorticoid therapy

Prednisone (Sterapred)

Targeted therapy

Alemtuzumab (Campath)

A-D

Regimen

Chemotherapy

A-D-CMF

Regimen

Chemotherapy

Abiraterone & Enzalutamide

Regimen

Endocrine therapy

Abiraterone & Ipatasertib

Regimen

Endocrine therapy

Abiraterone (Zytiga)

Targeted therapy

Ipatasertib (GDC-0068)

Abiraterone, Radium-223, Prednisone

Regimen

Endocrine therapy

Radiotherapy

Radium-223 (Xofigo)

ABV

ABV: Adriamycin (Doxorubicin), Bleomycin, Vinblastine

Regimen

Chemotherapy

ABVP

ABVP: Adriamycin (Doxorubicin), Bleomycin, Vinblastine, Platinol (Cisplatin)

Regimen

Chemotherapy

AC-KP

Regimen

Chemotherapy

Targeted therapy

Pertuzumab (Perjeta)

Antibody-drug conjugate therapy

Trastuzumab emtansine (Kadcyla)

ddAC-KP

Regimen

Chemotherapy

Targeted therapy

Pertuzumab (Perjeta)

Antibody-drug conjugate therapy

Trastuzumab emtansine (Kadcyla)

Acalabrutinib & Venetoclax

Regimen

Targeted therapy

ACP

ACP: Atezolizumab, Carboplatin, Paclitaxel

Regimen

Immunotherapy

Atezolizumab (Tecentriq)

Chemotherapy

AD-CMF

Regimen

Chemotherapy

Afatinib & Vinorelbine

Regimen

Chemotherapy

Vinorelbine (Navelbine)

Targeted therapy

Afatinib (Gilotrif)

A-ICE

A-ICE: ATRA, Idarubicin, Cytarabine, Etoposide

Regimen

Targeted therapy

All-trans retinoic acid (ATRA)

Chemotherapy

Altretamine & Melphalan

Regimen

Chemotherapy

AME

AME: Ara-C (Cytarabine), Mitoxantrone, Etoposide

Regimen

Chemotherapy

API

API: Adriamycin (Doxorubicin), Platinol (Cisplatin), Ifosfamide

Regimen

Chemotherapy

Amrubicin & Cisplatin

Regimen

Chemotherapy

Amsacrine monotherapy

Regimen

Chemotherapy

Amsacrine (Amsidine)

Amsacrine & Cytarabine

Regimen

Chemotherapy

Amsacrine & IDAC

Amsacrine & IDAC: Amsacrine & Intermediate Dose Ara-C (Cytarabine)

Regimen

Chemotherapy

Anastrozole and Everolimus

Regimen

Endocrine therapy

Anastrozole (Arimidex)

Targeted therapy

Everolimus (Afinitor)

Anastrozole and Lapatinib

Regimen

Endocrine therapy

Anastrozole (Arimidex)

Targeted therapy

Lapatinib (Tykerb)

Anastrozole and Tamoxifen

Regimen

Endocrine therapy

Anlotinib monotherapy

Regimen

Targeted therapy

Anlotinib (Fukewei)

ATRA, Cytarabine, Etoposide

Regimen

Targeted therapy

All-trans retinoic acid (ATRA)

Chemotherapy

AVML

AVML: Ara-C (Cytarabine), Vincristine, Methotrexate, Leucovorin

Regimen

Chemotherapy

Supportive therapy

Leucovorin (Folinic acid)

Axitinb & Toripalimab

Regimen

Immunotherapy

Toripalimab (Loqtorzi)

Targeted therapy

Axitinib (Inlyta)

Azacitidine & Eltrombopag

Regimen

Chemotherapy

Azacitidine (Vidaza)

Growth factor therapy

Eltrombopag (Promacta)

Azacitidine & Gilteritinib

Regimen

Chemotherapy

Azacitidine (Vidaza)

Targeted therapy

Gilteritinib (Xospata)

Binimetinib monotherapy

Regimen

Targeted therapy

Binimetinib (Mektovi)

Bortezomib & Bevacizumab

Regimen

Study	Dates of enrollment	Evidence	Comparator	Comparative Efficacy
White et al. 2012 (AMBER)	2007-2009	Randomized Phase 2 (E-esc)	Bortezomib	Did not meet primary endpoint of PFS (HR 0.74, 95% CI 0.43-1.28)

Targeted therapy

Bortezomib & Siltuximab

Regimen

Study	Dates of enrollment	Evidence	Comparator	Comparative Efficacy
Orlowski et al. 2015 (CR012784)	2006-2009	Randomized Phase 2 (E-esc)	Bortezomib	Did not meet primary endpoint of PFS (HR 0.87, 95% CI 0.65-1.16)

Targeted therapy

Bortezomib (Velcade)

Immunosuppressive therapy

Siltuximab (Sylvant)

BTH (Docetaxel)

BTH: Bevacizumab, Taxotere (Docetaxel), Herceptin (Trastuzumab)

Regimen

Chemotherapy

Docetaxel (Taxotere)

Targeted therapy

BTOC

BTOC: BCNU, Thiotepa, Oncovin (Vincristine), Cyclophosphamide

Regimen

Chemotherapy

CAD

CAD: Cyclophosphamide, Adriamycin (Doxorubicin), DDP (Cisplatin)

Regimen

Chemotherapy

Capecitabine & Cisplatin (CX) & Bevacizumab

Regimen

Chemotherapy

Targeted therapy

Bevacizumab (Avastin)

Capecitabine & Cisplatin (CX) & Ramucirumab

Regimen

Chemotherapy

Targeted therapy

Ramucirumab (Cyramza)

Capecitabine & Ruxolitinib

Regimen

Chemotherapy

Capecitabine (Xeloda)

Targeted therapy

Ruxolitinib (Jakafi)

Capecitabine & Sorafenib

Regimen

Chemotherapy

Capecitabine (Xeloda)

Targeted therapy

Sorafenib (Nexavar)

Capecitabine & Sunitinib

Regimen

Chemotherapy

Capecitabine (Xeloda)

Targeted therapy

Sunitinib (Sutent)

Capecitabine & Vinflunine

Regimen

Chemotherapy

Capecitabine & Vinorelbine (NX)

NX: Navelbine (Vinorelbine) & Xeloda (Capecitabine)

Regimen

Chemotherapy

Capecitabine, Cisplatin, Cetuximab, RT

Regimen

Chemotherapy

Targeted therapy

Cetuximab (Erbitux)

Radiotherapy

Concurrent radiation therapy

Capecitabine, Erlotinib, RT

Regimen

Capivasertib & Fulvestrant

Regimen

Endocrine therapy

Fulvestrant (Faslodex)

Targeted therapy

Capivasertib (Truqap)

CarboMIP

CarboMIP: Carboplatin, Mitomycin, Ifosfamide, Platinol (Cisplatin)

Regimen

Chemotherapy

Carboplatin & Epirubicin

Regimen

Chemotherapy

Carboplatin & Gemcitabine (GCb) & Gefitinib

Regimen

Chemotherapy

Targeted therapy

Gefitinib (Iressa)

Carboplatin & Paclitaxel (CP) & Bexarotene

CP & Bexarotene: Carboplatin, Paclitaxel, Bexarotene

Regimen

Chemotherapy

Targeted therapy

Bexarotene (Targretin)

Carboplatin & Paclitaxel (CP) & Cetuximab

CP & Cetuximab: Carboplatin, Paclitaxel, Cetuximab

Regimen

Chemotherapy

Targeted therapy

Cetuximab (Erbitux)

Carboplatin & Paclitaxel (CP) & Erlotinib

CP & Erlotinib: Carboplatin, Paclitaxel, Erlotinib

Regimen

Chemotherapy

Targeted therapy

Erlotinib (Tarceva)

Carboplatin & Paclitaxel (CP) & Pegylated liposomal doxorubicin

CP & PLD: Carboplatin, Paclitaxel, Pegylated Liposomal Doxorubicin
TC & PLD: Taxol (Paclitaxel), Carboplatin, Pegylated Liposomal Doxorubicin

Regimen

Chemotherapy

Carboplatin & Paclitaxel (CP) & Sorafenib

CP & Sorafenib: Carboplatin, Paclitaxel, Sorafenib

Regimen

Chemotherapy

Targeted therapy

Sorafenib (Nexavar)

Carboplatin & Paclitaxel (CP) & Topotecan

TC & Topotecan: Taxol (Paclitaxel), Carboplatin, Topotecan

Regimen

Chemotherapy

Carboplatin & Topotecan

Regimen

Chemotherapy

CBM

CBM: Capecitabine, Bevacizumab, Mitomycin

Regimen

Chemotherapy

Targeted therapy

Bevacizumab (Avastin)

CCG

CCG: Cisplatin, Carboplatin, Gemcitabine

Regimen

Chemotherapy

Carboplatin & Etoposide (CE) & Ipilimumab

CE & Ipilimumab: Carboplatin, Etoposide, Ipilimumab

Regimen

Chemotherapy

Immunotherapy

Ipilimumab (Yervoy)

Carboplatin & Etoposide (CE) & Thalidomide

CE & Thalidomide: Carboplatin, Etoposide, Thalidomide

Regimen

Chemotherapy

Targeted therapy

Thalidomide (Thalomid)

ChlVPP/EVA

ChlVPP/EVA: Chlorambucil, Vinblastine, Procarbazine, Prednisone alternating with Etoposide, Vincristine, Adriamycin (Doxorubicin)

Regimen

Chemotherapy, ChlVPP portion

Glucocorticoid therapy, ChlVPP portion

Prednisolone (Millipred)

Chemotherapy, EVA portion

CIB

CIB: Cisplatin, Ifosfamide, Bleomycin

Regimen

Chemotherapy

Cisplatin & Gemcitabine (GC) & Erlotinib

GC & Erlotinib: Gemcitabine, Cisplatin, Erlotinib

Regimen

Chemotherapy

Targeted therapy

Erlotinib (Tarceva)

Cisplatin & Gemcitabine (GC) & Gefitinib

GC & Gefitinib: Gemcitabine, Cisplatin, Gefitinib

Regimen

Chemotherapy

Targeted therapy

Gefitinib (Iressa)

Cisplatin & Gemcitabine (GC) & Nadroparin

GC & Nadroparin: Gemcitabine, Cisplatin, Nadroparin

Regimen

Chemotherapy

Anticoagulation

Nadroparin (Fraxiparine)

Cisplatin & Gemcitabine (GC) & Sorafenib

GC & Sorafenib: Gemcitabine, Cisplatin, Sorafenib

Regimen

Chemotherapy

Targeted therapy

Sorafenib (Nexavar)

Cisplatin & Gemcitabine (GC) & Tislelizumab

GC & Tislelizumab: Gemcitabine, Cisplatin, Tislelizumab

Regimen

Chemotherapy

Immunotherapy

Tislelizumab (Baizean)

Cisplatin & Methotrexate

Regimen

Chemotherapy

Cisplatin & Treosulfan

Regimen

Chemotherapy

Cisplatin & Vincristine

Regimen

Chemotherapy

Cisplatin, Avelumab, RT

Regimen

Chemotherapy

Cisplatin (Platinol)

Immunotherapy

Avelumab (Bavencio)

Radiotherapy

Concurrent radiation therapy

Cisplatin, Pemetrexed, Gefitinib

Regimen

Study	Dates of enrollment	Evidence	Comparator	Comparative Efficacy
Soria et al. 2015 (IMPRESS)	2012-2013	Phase 3 (E-esc)	Cisplatin & Pemetrexed	Did not meet primary endpoint of PFS Median PFS: 5.4 vs 5.4 mo (HR 0.86, 95% CI 0.65-1.13)

Chemotherapy

Targeted therapy

Gefitinib (Iressa)

Cisplatin, Pemetrexed, RT

Regimen

Chemotherapy

Radiotherapy

Concurrent radiation therapy

CODE

CODE: Cisplatin, Oncovin (Vincristine), Doxorubicin, Etoposide

Regimen

Chemotherapy

COPPEBVCAD

COPPEBVCAD: Cyclophosphamide, Oncovin (Vincristine), Procarbazine, Prednisone, Epirubicin, Bleomycin, Vinblastine, CCNU (Lomustine), Alkeran (Melphalan), DVA (Vindesine)

Regimen

Chemotherapy

Glucocorticoid therapy

Prednisone (Sterapred)

CYVADIC

CYVADIC: CYclophosphamide, Vincristine, ADriamycin (Doxorubicin), Imidazole Carboxamide (Dacarbazine)

Regimen

Chemotherapy

Dacarbazine & Dactinomycin

Regimen

Chemotherapy

Dacarbazine & Fotemustine

Regimen

Chemotherapy

Dacarbazine & Interferon alfa-2b

Regimen

Chemotherapy

Dacarbazine (DTIC)

Immunotherapy

Interferon alfa-2b (Intron-A)

Dacarbazine & Selumetinib

Regimen

Chemotherapy

Dacarbazine (DTIC)

Targeted therapy

Selumetinib (Koselugo)

Dacarbazine & Vindesine

Regimen

Chemotherapy

Dacarbazine, Fluorouracil, Semustine

Regimen

Chemotherapy

Dacarbazine, Fluorouracil, Semustine, Vincristine

Regimen

Chemotherapy

Dacarbazine, Fotemustine, Interferon alfa-2b

Regimen

Chemotherapy

Immunotherapy

Interferon alfa-2b (Intron-A)

Dacarbazine, Interferon alfa-2b, Tamoxifen

Regimen

Chemotherapy

Dacarbazine (DTIC)

Endocrine therapy

Tamoxifen (Nolvadex)

Immunotherapy

Interferon alfa-2b (Intron-A)

Dactinomycin, Doxorubicin, Vincristine

Regimen

Chemotherapy

DBCT

DBCT: Dacarbazine, BCNU (Carmustine), Cisplatin, Tamoxifen

Regimen

Chemotherapy

Endocrine therapy

Tamoxifen (Nolvadex)

Docetaxel & Erlotinib

Regimen

Chemotherapy

Docetaxel (Taxotere)

Targeted therapy

Erlotinib (Tarceva)

Docetaxel & Fluorouracil

Regimen

Chemotherapy

Docetaxel & Gefitinib

Regimen

Chemotherapy

Docetaxel (Taxotere)

Targeted therapy

Gefitinib (Iressa)

Docetaxel & Lapatinib (TL)

Regimen

Chemotherapy

Docetaxel (Taxotere)

Targeted therapy

Lapatinib (Tykerb)

Docetaxel & Leuprolide

Regimen

Chemotherapy

Docetaxel (Taxotere)

Endocrine therapy

Leuprolide (Lupron)

Docetaxel & Pertuzumab

Regimen

Chemotherapy

Docetaxel (Taxotere)

Targeted therapy

Pertuzumab (Perjeta)

Docetaxel & Selumetinib

Regimen

Chemotherapy

Docetaxel (Taxotere)

Targeted therapy

Selumetinib (Koselugo)

Docetaxel & Sunitinib

Regimen

Chemotherapy

Docetaxel (Taxotere)

Targeted therapy

Sunitinib (Sutent)

Docetaxel & Ziv-aflibercept

Regimen

Chemotherapy

Docetaxel (Taxotere)

Targeted therapy

Ziv-aflibercept (Zaltrap)

Docetaxel, Lenalidomide, Prednisone

Regimen

Chemotherapy

Docetaxel (Taxotere)

Endocrine therapy

Prednisone (Sterapred)

Targeted therapy

Lenalidomide (Revlimid)

Docetaxel, Prednisone, Bevacizumab

Regimen

Chemotherapy

Docetaxel (Taxotere)

Endocrine therapy

Prednisone (Sterapred)

Targeted therapy

Bevacizumab (Avastin)

Doxorubicin & Etoposide

Regimen

Chemotherapy

Doxorubicin & Paclitaxel

Regimen

Chemotherapy

Doxorubicin & Sorafenib

Regimen

Chemotherapy

Doxorubicin (Adriamycin)

Targeted therapy

Sorafenib (Nexavar)

Doxorubicin & Streptozocin

Regimen

Chemotherapy

Doxorubicin & Vinblastine (AV)

AV: Adriamycin (Doxorubicin) & Vinblastine

Regimen

Chemotherapy

Doxorubicin & Vinorelbine

Regimen

Chemotherapy

EAP

EAP: Etoposide, Adriamycin (Doxorubicin), Platinol (Cisplatin)

Regimen

Chemotherapy

ECVBP

ECVBP: Epirubicin, Cyclophosphamide, Vindesine, Bleomycin, Prednisone

Regimen

Chemotherapy

Glucocorticoid therapy

Prednisone (Sterapred)

ECX & Bevacizumab

Regimen

Chemotherapy

Targeted therapy

Bevacizumab (Avastin)

EC-KP

Regimen

Chemotherapy

Targeted therapy

Pertuzumab (Perjeta)

Antibody-drug conjugate therapy

Trastuzumab emtansine (Kadcyla)

ddEC-KP

Regimen

Chemotherapy

Targeted therapy

Pertuzumab (Perjeta)

Antibody-drug conjugate therapy

Trastuzumab emtansine (Kadcyla)

EC-TL (Docetaxel)

EC-TL: Epirubicin & Cyclophosphamide, followed by Taxotere (Docetaxel) & Lapatinib
EC-DL: Epirubicin & Cyclophosphamide, followed by Docetaxel & Lapatinib

Regimen

Chemotherapy, EC portion

Chemotherapy, TL portion

Docetaxel (Taxotere)

Targeted therapy, TL portion

Lapatinib (Tykerb)

ELF

ELF: Etoposide, Leucovorin, 5-FU (Fluorouracil)

Regimen

Chemotherapy

ELFE

ELFE: Etoposide, Leucovorin, 5-FU (Fluorouracil), Epirubicin

Regimen

Chemotherapy

Encorafenib monotherapy

Regimen

Targeted therapy

Encorafenib (Braftovi)

EP & Ipilimumab

EP & Ipilimumab: Etoposide, Platinol (Cisplatin), Ipilimumab

Regimen

Chemotherapy

Immunotherapy

Ipilimumab (Yervoy)

EP, Tamoxifen, RT

EP, Tamoxifen, RT: Etoposide, Platinol (Cisplatin), Tamoxifen, Radiation Therapy

Regimen

Chemotherapy

Endocrine therapy

Tamoxifen (Nolvadex)

Radiotherapy

Concurrent thoracic radiation therapy

Erlotinib & Sorafenib

Regimen

Targeted therapy

Erlotinib & Sunitinib

Regimen

Targeted therapy

Erlotinib, Bevacizumab, Panitumumab

Regimen

Targeted therapy

Erlotinib, Gemcitabine, Bevacizumab

Regimen

Chemotherapy

Gemcitabine (Gemzar)

Targeted therapy

Everolimus & Letrozole

Regimen

Endocrine therapy

Letrozole (Femara)

Targeted therapy

Everolimus (Afinitor)

Everolimus & Paclitaxel

Regimen

Chemotherapy

Paclitaxel (Taxol)

Targeted therapy

Everolimus (Afinitor)

Everolimus & Sorafenib

Regimen

Targeted therapy

Everolimus & Vinorelbine

Regimen

Chemotherapy

Vinorelbine (Navelbine)

Targeted therapy

Everolimus (Afinitor)

Exemestane & Lapatinib

Regimen

Endocrine therapy

Exemestane (Aromasin)

Targeted therapy

Lapatinib (Tykerb)

Exemestane & Palbociclib

Regimen

Endocrine therapy

Exemestane (Aromasin)

Targeted therapy

Palbociclib (Ibrance)

E-GEMOX

E-GEMOX: Erlotinib, GEMcitabine, OXaliplatin

Regimen

Targeted therapy

Erlotinib (Tarceva)

Chemotherapy

FAP

FAP: Fluorouracil, Alfa interferon, Platinol (Cisplatin)

Regimen

Chemotherapy

Immunotherapy

Interferon alfa-2b (Intron-A)

FEC & HP

FEC & HP: Fluorouracil, Epirubicin, Cyclophosphamide, Herceptin (Trastuzumab), Pertuzumab

Regimen

Chemotherapy

Targeted therapy

ddFEC

ddFEC: dose-dense Fluorouracil, Epirubicin, Cyclophosphamide

Regimen

Chemotherapy

Growth factor therapy

G-CSF

FLA

FLA: FLudarabine & Ara-C (Cytarabine)

Regimen

Chemotherapy

FLAG-Ida & GO

FLAG-Ida & GO: FLudarabine, Ara-C (Cytarabine), G-CSF (Lenograstim), Idarubicin, Gemtuzumab Ozogamicin

Regimen

Chemotherapy

Fludarabine (Fludara) 30 mg/m² IV once per day on days 2 to 6
Cytarabine (Ara-C) 2000 mg/m² IV over 4 hours once per day on days 2 to 6, given 4 hours after fludarabine
Idarubicin (Idamycin) 8 mg/m² IV once per day on days 4 to 6

Growth factor therapy

Lenograstim (Granocyte)

Antibody-drug conjugate therapy

Gemtuzumab ozogamicin (Mylotarg)

FLAI

FLAI: FLudarabine, Ara-C (Cytarabine), Idarubicin
FIA: Fludarabine, Idarubicin, Ara-C (Cytarabine)

Regimen

Chemotherapy

FOLF-CB

FOLF-CB: FOLinic acid (Leucovorin), Fluorouracil, Cetuximab, Bevacizumab

Regimen

Chemotherapy

Targeted therapy

FOLFIRI & Regorafenib

FOLFIRI & Regorafenib: FOLinic acid (Leucovorin), Fluorouracil, IRInotecan, Regorafenib

Regimen

Chemotherapy

Targeted therapy

Regorafenib (Stivarga)

FOLFIRI & Simvastatin

FOLFIRI & Simvastatin: FOLinic acid (Leucovorin), Fluorouracil, IRInotecan, Simvastatin

Regimen

Chemotherapy

Targeted therapy

Simvastatin (Zocor)

FOLFIRI & Sunitinib

FOLFIRI & Sunitinib: FOLinic acid (Leucovorin), Fluorouracil, IRInotecan, Sunitinib

Regimen

Chemotherapy

Targeted therapy

Sunitinib (Sutent)

FULV & Cisplatin

FULV & Cisplatin: 5-FU, LeucoVorin, Cisplatin

Regimen

Chemotherapy

FULV & Edrecolomab

FULV & Edrecolomab: 5-FU, LeucoVorin, Edrecolomab

Regimen

Chemotherapy

Targeted therapy

Edrecolomab (Panorex)

FULV & Interferon alfa-2a

FULV & Interferon alfa-2a: 5-FU, LeucoVorin, Interferon alfa-2a

Regimen

Chemotherapy

Immunotherapy

Interferon alfa-2a (Roferon-A)

FULV & Interferon alfa-2b

FULV & Interferon alfa-2b: 5-FU, LeucoVorin, Interferon alfa-2b

Regimen

Chemotherapy

Immunotherapy

Interferon alfa-2b (Intron-A)

FULV & Interferon alfa-2c

FULV & Interferon alfa-2c: 5-FU, LeucoVorin, Interferon alfa-2c

Regimen

Chemotherapy

Immunotherapy

Interferon alfa-2c (Berofor)

FULV & Trimetrexate

FULV & Trimetrexate: 5-FU, LeucoVorin, Trimetrexate

Regimen

Chemotherapy

GVP

GVP: Gemcitabine, Vinorelbine, Platinol (Cisplatin)

Regimen

Chemotherapy

ICE, ATRA, GO

ICE, ATRA, GO: Idarubicin, Cytarabine, Etoposide, All-Trans Retinoic Acid, Gemtuzumab Ozogamicin

Regimen

Chemotherapy

Targeted therapy

All-trans retinoic acid (ATRA)

Antibody-drug conjugate therapy

Gemtuzumab ozogamicin (Mylotarg)

Ixabepilone & Bevacizumab

Regimen

Chemotherapy

Ixabepilone (Ixempra)

Targeted therapy

Bevacizumab (Avastin)

ME

ME: Mitoxantrone & Etoposide

Regimen

Chemotherapy

MEV

MEV: Mitomycin, Etoposide, Vindesine

Regimen

Chemotherapy

MFL

MFL: Methyl-lomustine (MeCCNU), 5-FU, Leucovorin

Regimen

Chemotherapy

MFT

MFL: Methotrexate, 5-FU, Tamoxifen

Regimen

Chemotherapy

Endocrine therapy

Tamoxifen (Nolvadex)

Mitoxantrone & Hydrocortisone

Regimen

Chemotherapy

Mitoxantrone (Novantrone)

Endocrine therapy

Hydrocortisone (Cortef)

MMF

MMF: Methyl-lomustine (MeCCNU), Mitomycin, 5-FU

Regimen

Chemotherapy

MOPPEBVCAD

MOPPEBVCAD: Mechlorethamine, Oncovin (Vincristine), Procarbazine, Prednisone, Epirubicin, Bleomycin, Vinblastine, CCNU (Lomustine), Adriamycin (Doxorubicin), DVA (Vindesine)