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Cediranib (Recentin)

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=Preliminary data=
==[[Colon cancer]]==
* '''HORIZON II:''' Hoff PM, Hochhaus A, Pestalozzi BC, Tebbutt NC, Li J, Kim TW, Koynov KD, Kurteva G, Pintér T, Cheng Y, van Eyll B, Pike L, Fielding A, Robertson JD, Saunders MP. Cediranib plus FOLFOX/CAPOX versus placebo plus FOLFOX/CAPOX in patients with previously untreated metastatic colorectal cancer: a randomized, double-blind, phase III study (HORIZON II). J Clin Oncol. 2012 Oct 10;30(29):3596-603. Epub 2012 Sep 10. [http://jco.ascopubs.org/content/30/29/3596.long link to original article] '''contains verified protocol''' [https://www.ncbi.nlm.nih.gov/pubmed/22965965 PubMed]* '''HORIZON III:''' Schmoll HJ, Cunningham D, Sobrero A, Karapetis CS, Rougier P, Koski SL, Kocakova I, Bondarenko I, Bodoky G, Mainwaring P, Salazar R, Barker P, Mookerjee B, Robertson J, Van Cutsem E. Cediranib with mFOLFOX6 versus bevacizumab with mFOLFOX6 as first-line treatment for patients with advanced colorectal cancer: a double-blind, randomized phase III study (HORIZON III). J Clin Oncol. 2012 Oct 10;30(29):3588-95. Epub 2012 Sep 10. [http://jco.ascopubs.org/content/30/29/3588.long link to original article] [https://www.ncbi.nlm.nih.gov/pubmed/22965961 PubMed]
==[[Ovarian cancer]]==
* '''ICON6:''' Ledermann JA, Embleton AC, Raja F, Perren TJ, Jayson GC, Rustin GJS, Kaye SB, Hirte H, Eisenhauer E, Vaughan M, Friedlander M, González-Martín A, Stark D, Clark E, Farrelly L, Swart AM, Cook A, Kaplan RS, Parmar MKB; ICON6 collaborators. Cediranib in patients with relapsed platinum-sensitive ovarian cancer (ICON6): a randomised, double-blind, placebo-controlled phase 3 trial. Lancet. 2016 Mar 12;387(10023):1066-1074. Erratum in: Lancet. 2016 Apr 23;387(10029):1722. [https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(15)01167-8/fulltext link to original article] [https://www.ncbi.nlm.nih.gov/pubmed/27025186 PubMed]
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