Class/mechanism: Hedgehog pathway inhibitor. Sonidegib binds to and inhibits the transmembrane protein Smoothened (SMO), which is part of the Hedgehog signal transduction pathway that is clinically relevant in diseases such as basal cell cancer.
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Diseases for which it is used
Patient drug information
History of changes in FDA indication
Also known as
- Code name: LDE225
- Generic name: erismodegib
- Brand name: Odomzo