Olanzapine (Zyprexa)

Mechanism of action

Atypical antipsychotic with antiemetic properties, likely through its effect on dopamine receptors. No known antineoplastic properties.

History of changes in PMDA indication

• 2017-12-25: New additional indication and a new dosage indicated for the treatment of gastrointestinal symptoms (nausea and vomiting) associated with the administration of antineoplastic drugs (cisplatin, etc.).

Also known as

• Brand name: Zyprexa