Octreotide LAR (Sandostatin LAR)
Class/mechanism: Long-acting dosage form of Octreotide (Sandostatin). The LAR depot formulation consists of octreotide contained within biodegradable glucose star polymer microspheres; octreotide is gradually released as the polymer degrades via hydrolysis. Octreotide (Sandostatin) is a long-acting octapeptide that suppresses multiple hormones and has physiologic actions similar to somatostatin. It suppresses LH response to GnRH, reduces splanchnic blood flow, and inhibits release of serotonin, gastrin, vasoactive intestinal peptide, secretin, motilin, pancreatic polypeptide, growth hormone, IGF-I (somatomedin C), glucagon, insulin, and TSH.
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Diseases for which it is used
Patient drug information
Also known as
- Generic names: octreotide acetate for injectable suspension, octreotide long-acting release
- Brand names: Longastatina LAR, Sandostatin LAR, Sandostatin LAR Depot, Sandostatina LAR, Sandostatine LAR