Class/mechanism: Superparamagnetic iron oxide that is coated with a carbohydrate shell, which isolates the iron from plasma components until the iron-carbohydrate complex enters the reticuloendothelial system macrophages of the liver, spleen, and bone marrow. Iron is released from the iron-carbohydrate complex within vesicles in the macrophages.
Extravasation: no information
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Patient drug information
History of changes in FDA indication
- 6/30/2009: Initial FDA approval "for the treatment of iron deficiency anemia in adult patients with chronic kidney disease (CKD)."
Also known as
- Brand name: Feraheme