Class/mechanism: 5 alpha-reductase inhibitor; inhibits conversion of testosterone to dihydrotestosterone (DHT). Competitively inhibits type 1 and 2 5 alpha-reductase isoenzymes by forming a stable enzyme complex with them.
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Diseases for which it is used
Patient drug information
History of changes in FDA indication
- 11/20/2001: Initial FDA approval "for the treatment of symptomatic benign prostatic hyperplasia (BPH) in men with an enlarged prostate gland."
- 6/9/2011: New FDA Limitation of Use: "AVODART is not approved for the prevention of prostate cancer."
Also known as
- Brand name: Avodart