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Alpelisib (Piqray)

Contents

Mechanism of action

From NCI Drug Dictionary: An orally bioavailable phosphatidylinositol 3-kinase (PI3K) inhibitor with potential antineoplastic activity. Alpelisib specifically inhibits PIK3 in the PI3K/AKT kinase (or protein kinase B) signaling pathway, thereby inhibiting the activation of the PI3K signaling pathway. This may result in inhibition of tumor cell growth and survival in susceptible tumor cell populations.

Diseases for which it is used

Patient drug information

To be completed

History of changes in FDA indication

Also known as

  • Code name: BYL719
  • Brand name: Piqray

References