Difference between revisions of "Avatrombopag (Doptelet)"
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Warner-admin (talk | contribs) m (Text replacement - "Category:Autoimmune thrombocytopenic purpura" to "Category:Immune thrombocytopenia") |
Warner-admin (talk | contribs) m (Text replacement - "Autoimmune thrombocytopenic purpura (ITP)" to "Immune thrombocytopenia (ITP)") |
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==Diseases for which it is used== | ==Diseases for which it is used== | ||
| − | *[[ | + | *[[Immune thrombocytopenia (ITP)]] |
# Bussel JB, Kuter DJ, Aledort LM, Kessler CM, Cuker A, Pendergrass KB, Tang S, McIntosh J. A randomized trial of avatrombopag, an investigational thrombopoietin-receptor agonist, in persistent and chronic immune thrombocytopenia. Blood. 2014 Jun 19;123(25):3887-94. Epub 2014 May 6. [http://bloodjournal.hematologylibrary.org/content/123/25/3887.long link to original article] [https://www.ncbi.nlm.nih.gov/pubmed/24802775 PubMed] | # Bussel JB, Kuter DJ, Aledort LM, Kessler CM, Cuker A, Pendergrass KB, Tang S, McIntosh J. A randomized trial of avatrombopag, an investigational thrombopoietin-receptor agonist, in persistent and chronic immune thrombocytopenia. Blood. 2014 Jun 19;123(25):3887-94. Epub 2014 May 6. [http://bloodjournal.hematologylibrary.org/content/123/25/3887.long link to original article] [https://www.ncbi.nlm.nih.gov/pubmed/24802775 PubMed] | ||
*[[Thrombocytopenia in liver disease]] | *[[Thrombocytopenia in liver disease]] | ||
Revision as of 01:51, 24 July 2018
Mechanism of action
Thrombopoietin receptor agonist
Diseases for which it is used
- Bussel JB, Kuter DJ, Aledort LM, Kessler CM, Cuker A, Pendergrass KB, Tang S, McIntosh J. A randomized trial of avatrombopag, an investigational thrombopoietin-receptor agonist, in persistent and chronic immune thrombocytopenia. Blood. 2014 Jun 19;123(25):3887-94. Epub 2014 May 6. link to original article PubMed
History of changes in FDA indication
- 5/21/2018: FDA approved "for thrombocytopenia in adults with chronic liver disease scheduled to undergo a procedure."
Also known as
- Code names: E5501, YM477, AKR 501
- Brand name: Doptelet