Factor VIII, human and recombinant (antihemophilic factor 8)
Also known as Advate rAHF-PFM, coagulation factor 8, Helixate, Helixate FS, Hemofil-M, Koate-DVI, Koate-HP, Kogenate, Kogenate FS, Monarc-M, Monoclate-P, Recombinate, Refacto, or Xyntha.
Contents |
General information
Class/mechanism: Factor VIII; replaces the missing clotting factor VIII that is required for hemostasis in patients with hemophilia A.
Please choose from the products below to find specific drug/manufacturer information:
- Advate (recombinant) [1][2][3]
- Helixate FS (recombinant) [4][5][6]
- Hemofil-M (human)[7][8][9]
- Koate-DVI (human)[10][11][12]
- Kogenate FS (recombinant)[13][14][15]
- Monarc-M (human)[16][17]
- Monoclate-P (human)[18][19][20]
- Recombinate (recombinant)[21][22][23]
- ReFacto (recombinant)[24][25]
- Xyntha (recombinant)[26][27][28]
Route: IV
Extravasation: no information
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the prescribing information.
Diseases for which it is used
- Hemophilia A
Patient drug information
- Factor VIII, recombinant (Advate) package insert PDF pages 7-8[2]
- Factor VIII, recombinant (Helixate FS) package insert PDF pages 14-18[5]
- Factor VIII, recombinant (Kogenate FS) package insert PDF pages 16-21[14]
- Factor VIII, recombinant (Recombinate) package insert PDF pages 15-24[22]
- Factor VIII, recombinant (ReFacto) package insert PDF pages 11-14[24]
- Factor VIII, recombinant (Xyntha) package insert PDF pages 22-30[27]
- Factor VIII, recombinant (antihemophilic factor 8) patient drug information (UpToDate)[29]
References
- ↑ Advate manufacturer's website
- ↑ 2.0 2.1 Factor VIII, recombinant (Advate) package insert
- ↑ Factor VIII, recombinant (Advate) package insert (locally hosted backup)
- ↑ Helixate FS manufacturer's website
- ↑ 5.0 5.1 Factor VIII, recombinant (Helixate FS) package insert
- ↑ Factor VIII, recombinant (Helixate FS) package insert (locally hosted backup)
- ↑ Hemofil-M manufacturer's website
- ↑ Factor VIII, human (Hemofil-M) package insert
- ↑ Factor VIII, human (Hemofil-M) package insert (locally hosted backup)
- ↑ Koate-DVI manufacturer's website
- ↑ Factor VIII, human (Koate-DVI) package insert
- ↑ Factor VIII, human (Koate-DVI) package insert (locally hosted backup)
- ↑ Kogenate FS manufacturer's website
- ↑ 14.0 14.1 Factor VIII, recombinant (Kogenate FS) package insert
- ↑ Factor VIII, recombinant (Kogenate FS) package insert (locally hosted backup)
- ↑ Factor VIII, human (Monarc-M) package insert
- ↑ Factor VIII, human (Monarc-M) package insert (locally hosted backup)
- ↑ Monoclate-P manufacturer's website
- ↑ Factor VIII, human (Monoclate-P) package insert
- ↑ Factor VIII, human (Monoclate-P) package insert (locally hosted backup)
- ↑ Recombinate manufacturer's website
- ↑ 22.0 22.1 Factor VIII, recombinant (Recombinate) package insert
- ↑ Factor VIII, recombinant (Recombinate) package insert (locally hosted backup)
- ↑ 24.0 24.1 Factor VIII, recombinant (ReFacto) package insert
- ↑ Factor VIII, recombinant (ReFacto) package insert (locally hosted backup)
- ↑ Xyntha manufacturer's website
- ↑ 27.0 27.1 Factor VIII, recombinant (Xyntha) package insert
- ↑ Factor VIII, recombinant (Xyntha) package insert (locally hosted backup)
- ↑ Factor VIII, recombinant (antihemophilic factor 8) patient drug information (UpToDate)
