Aspirin

General information

Class/mechanism: Irreversible inhibitor of prostaglandin cyclooxygenase and the production of thromboxane A2 (platelet aggregation factor). Additional effects are dose-dependent and include inhibiting production of prostaglandin I2 (prostacyclin). Higher doses of aspirin have anti-inflammatory effects, in part from inhibiting cyclooxygenase.
Route: PO
Extravasation: n/a

For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, Medscape, UpToDate (courtesy of Lexicomp), or the prescribing information.

Diseases for which it is used

• Antiphospholipid antibody syndrome
• Essential thrombocythemia
• Polycythemia vera
• Venous thromboembolism

Patient drug information

• Aspirin patient drug information (UpToDate)

Also known as

• Generic names: A-A-S 500, A.A.S., A.S.A., AAC, AAS, Acetylsalicylate Calcium, Acetylsalicylate Copper, Acetylsalicylate Lysine, Acetylsalicylate Sodium, Acetylsalicylic Acid Aluminium, Acetylsalicylic Acid Effervescent, Acetylsalicylic Acid Enteric Coated, Acid Acetylsalicylic, Acido Acetilsalicilico, Acidum Acethylsalicylicum, Acidum Acetylsalicum, Acidum Acetylsalicylic, Acidum Acetylsalicylicum, Acidum Ascorbinicum, ASA, ASS, ECASA, Methyl Diethylacetylsalicylate, Aspirin
• Brand names: Acard, Acenterine, Acesal, Acesan, Acetard, Acetisal, Acetophen, Acetosal, Acetylsalicylsaeure, Acetylsalicylsyra, Acetylsalicylsyre, Acetylsalicylzuur, Acetylsalisylsyre, Acetysal, Acisal, Actispirine, Acylpyrin, Adiprin, Albyl, Albyl-Selters, Albyl Minor, Anbol, Ancasal, Andol, Angettes, Anopyrin, Artria-SR, Asacard, Asaferm, Asaflow, Asalent, Asalite, Asaphen, Asarid, Ascardia, Asdol, Aspecard, Aspent, Aspenter, Asperan, Aspergic, Aspergum, Aspeter, Aspilets, Aspirina-G, Aspirina, Aspirine, Aspirinetas, Aspirinetta, Aspirisucre, Aspirtab, Aspisol, Aspocid, Asprim, Asprimox ID, Aspro, Asrin, Astrix, Ataspin, Avasyl, Babyprin, Babypyrin, Baludon, Bamycor, Bamyl, Bamyl S, Bayaspirin, Bayaspirina, Bestpirin, Bioplak, Bokey EMC, Breoprin, Bufacyl, Buferin, Bufferin, Cafenol, Cafiaspirina, Caprin, Capsasal, Cardegic, Cardioaspirina, Cardioaspirine, Cardiopirin, Cardirene, Casprium, Catalgine, Catalgix, CC COR, Cebaspirine, Cemirit, Claradin, Claragine, Clariprin, Colfarit, Colsprin, Contra-Schmerz ASS, COR-30, Coraspin, Coraspirina, Corplus, Corsalbene, Coryphen, Delgesic, Demoprin Novum, Disperin, Dispril, Disprin, Disprina, Doloderm, Doloprin, Dolorosan, Draspir, Dulcipirina, Dusil, Easprin, Ecopirin, Ecoprin, Ecosprin, Ecotrin, Ecotrin 650, Ecotrin Maximum Strenght, Egicalm, Empirin, Encaprin, Encoprin, Enterosarine, Entrophen, Equate Daily, Fitoaspirin, Flectadol, Garaspirine, Geniol AP, Geniolito, Geniol SC, Geniol SC SIN Cafeina, Genprin, Globentyl, Godamed TAH, Halfprin, Herzass, Hjerdyl, Hjertealbyl, Huma ASA, Hybin, Junior Asprin, Jusprin, Karmyl, Kilios, Lasdol, Levius, Licyl, Lisaspin, LO-Aspirin, Lowasa, Lysoprin, Magnecyl, Measurin, Medi-RUB, Medisyl, Mejoral Infantil, Melhoral Infantil, Metaspirine, Micristin, Micropirin, Migraspirina, Miniasal, Minimax, Naspro, Nichiaspirin, Nova-Phase, Novasen, Novid, Pharmacin, Pharmaspirin, Phenaspirine, Platet, Polopiryna, Polopiryna S, Premaspin, Primaspan, Quinton, Remin S, Reumyl, Rhodine, Rhonal, Rhusal, Rivasa, Ronal, S.R.A., SAL-Adult, Salitison, Salospir, Salospir-A, Saspryl, Sinaspir, Solprin, Solpyron, Soluble AAC, Solusprin, Spren, Stanback, Stanback Analgesic, Supasa, Tampyrine, Thomapyrin Akut, Thrombace NEO, Thrombo, Thrombo AS, Thrombo ASS, Togal ASS, Toldex, Tooprin, Tromalyt, Trombyl, Uniaspirin, Upsalgina, Upsarin, Venopirin, Winsprin, Zenaspirin, Zoprin, Zorprin.