Alendronate (Fosamax)
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General information
Class/mechanism: Bisphosphonate, inhibits osteoclast activity, dissolution of hydroxyapatite crystals, and bone resorption/turnover.[1][2]
Route: PO
Extravasation: n/a
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, Medscape, UpToDate (courtesy of Lexicomp), or the prescribing information.[1]
Patient drug information
- Patient counseling information can be found on page 22-23 of the Alendronate (Fosamax) package insert[1]
- Alendronate (Fosamax) patient drug information (UpToDate)[3]
Also known as
- Generic names: acide alendronique, acido alendronico, alendronic acid
- Brand names:
| Synonyms | |||||||
|---|---|---|---|---|---|---|---|
| Adronat | Aidbone | Aldren | Aldronac | Alemax | Alenat | Alenato | Alenbon |
| Alend | Alendene | Alendex | Alendil | Alendomax | Alendon | Alendor | Alendra 7 |
| Alendral | Alendrate | Alendrin | Alendro | Alendromax | Alendron | Alendronat | Alendronato |
| Alendronhexal | Alendroninezr | Alendroninezuur | Alendronsaeure | Alendronstad | Alendros | Alenmax | Alenost |
| Alent | Alentop | Aliot | Allenmax | Alont | Alovell | Apodrolen | Arendal |
| Armol | Arond | Berlex | Bifemelan | Bifosa | Bifosmac | Binosto | Bisbon |
| Blindafe | Bolend | Bonaid | Bonalon | Bonamax | Bonapex | Bonemax | Bongard |
| Bonmax | Bonomax | Bostrong | Brek | Calidron | Cleveron | Defixal | Denfos |
| Drate | Dronadil | Dronal | Dronalent | Dronat | Drovitan | Durost | Elandur |
| Endronal | Endronax | Endrostan | Endrox | Eucalen | Findeclin | Firmofos | Fixopan |
| Folend | Forenmax | Fosaalen | Fosalan | Fosalen | Fosalong | Fosamac | Fosamax |
| Fosanet | Fosaqueen | Fosavance | Fosfalen | Fosfoplus | Fosmin | Fostepor | Fosval |
| Genalen | Genalmen | Gerical | Gynodron | Holadren | Lafedam | Landrolen | Lendronal |
| Leodrin | Lindron | Lokar | Marvil | Maxibone | Minusorb | Nichospor | Onclast |
| Orthonate | Osalen | Osaston | Osdronat | Oseolen | Oseomax | Oseotal | Oseotenk |
| Osficar | Oslene | Ossifix | Ossomax | Ostat | Ostel | Ostemax Comfort | Ostenan |
| Osteobon | Osteodur | Osteofar | Osteofel | Osteofene | Osteofos | Osteofose | Osteomax |
| Osteomed | Osteomel | Osteomepha | Osteomix | Osteonato | Osteoral | Osteotec | Osteotrat |
| Ostex | Ostolek | Ostonat | Oxtalen | Phostarac | Poris | Porosal | Porosin |
| Ralenost | Recalfe | Regenesis | Rekostin | Restofos | Reventa | Romax | Silidral |
| Sinfract | Synostep | Teiroc | Terost | Tevalen | Tevanate | Tibolene | Tibone |
| Tilios | Voroste | Zophost | |||||